Targeted mutations of the juxtamembrane tyrosines in the Kit receptor tyrosine kinase selectively affect multiple cell lineages

Loss-of-function mutations in the murine dominant white spotting/c-kit locus affect a diverse array of biological processes and cell lineages and cause a range of phenotypes, including severe anemia, defective pigmentation, sterility, mast cell deficits, a lack of interstitial cells of Cajal, spatia...

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Hlavní autoři: Kimura, Yuki, Jones, Nina, Klüppel, Michael, Hirashima, Masanori, Tachibana, Kazunobu, Cohn, Jason B., Wrana, Jeffrey L., Pawson, Tony, Bernstein, Alan
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2004
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC395915/
https://ncbi.nlm.nih.gov/pubmed/15067126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0305363101
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