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Membrane channel structure of Helicobacter pylori vacuolating toxin: Role of multiple GXXXG motifs in cylindrical channels

Helicobacter pylori is a human pathogen responsible for severe gastric diseases such as peptic ulcers, gastric adenocarcinoma, and gastric lymphoma. Vacuolating toxin (VacA) is crucial in facilitating the colonization of the gastric lining by inducing cell apoptosis and immune suppression. VacA inse...

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Main Authors: Kim, Sanguk, Chamberlain, Aaron K., Bowie, James U.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC395910/
https://ncbi.nlm.nih.gov/pubmed/15067113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308694101
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