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Heritable and inducible gene knockdown in astrocytes or neurons in vivo by a combined lentiviral and RNAi approach

Gene knockout by homologous recombination is a popular method to study gene functions in the mouse in vivo. However, its lack of temporal control has limited the interpretation of knockout studies because the complete elimination of a gene product often alters developmental processes, and can induce...

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Sonraí Bibleagrafaíochta
Main Authors: Heitz, Fabrice, Johansson, Torbjörn, Baumgärtel, Karsten, Gecaj, Rreze, Pelczar, Pawel, Mansuy, Isabelle M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958736/
https://ncbi.nlm.nih.gov/pubmed/24678290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00062
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