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Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehog

The differentiation of mesenchymal cells into chondrocytes and chondrocyte proliferation and maturation are fundamental steps in skeletal development. Runx2 is essential for osteoblast differentiation and is involved in chondrocyte maturation. Although chondrocyte maturation is delayed in Runx2-defi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yoshida, Carolina A., Yamamoto, Hiromitsu, Fujita, Takashi, Furuichi, Tatsuya, Ito, Kosei, Inoue, Ken-ichi, Yamana, Kei, Zanma, Akira, Takada, Kenji, Ito, Yoshiaki, Komori, Toshihisa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC395853/
https://ncbi.nlm.nih.gov/pubmed/15107406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1174704
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