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Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia

Facial abnormalities in human SHH mutants have implicated the Hedgehog (Hh) pathway in craniofacial development, but early defects in mouse Shh mutants have precluded the experimental analysis of this phenotype. Here, we removed Hh-responsiveness specifically in neural crest cells (NCCs), the multip...

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Bibliografiske detaljer
Main Authors: Jeong, Juhee, Mao, Junhao, Tenzen, Toyoaki, Kottmann, Andreas H., McMahon, Andrew P.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC395852/
https://ncbi.nlm.nih.gov/pubmed/15107405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1190304
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