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LKB1/AMPK and PKA Control ABCB11 Trafficking and Polarization in Hepatocytes

Polarization of hepatocytes is manifested by bile canalicular network formation and activation of LKB1 and AMPK, which control cellular energy metabolism. The bile acid, taurocholate, also regulates development of the canalicular network through activation of AMPK. In the present study, we used coll...

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Detalhes bibliográficos
Main Authors: Homolya, László, Fu, Dong, Sengupta, Prabuddha, Jarnik, Michal, Gillet, Jean-Pierre, Vitale-Cross, Lynn, Gutkind, J. Silvio, Lippincott-Schwartz, Jennifer, Arias, Irwin M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958433/
https://ncbi.nlm.nih.gov/pubmed/24643070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091921
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