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Quantitative Characterization of Defective Virus Emergence by Deep Sequencing
Populations of RNA viruses can spontaneously produce variants that differ in genome size, sequence, and biological activity. Defective variants that lack essential genes can nevertheless reproduce by coinfecting cells with viable virus, a process that interferes with virus growth. How such defective...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3958049/ https://ncbi.nlm.nih.gov/pubmed/24352442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02675-13 |
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