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IκB Kinase ε Targets Interferon Regulatory Factor 1 in Activated T Lymphocytes

IκB kinase ε (IKK-ε) has an essential role as a regulator of innate immunity, functioning downstream of pattern recognition receptors to modulate NF-κB and interferon (IFN) signaling. In the present study, we investigated IKK-ε activation following T cell receptor (TCR)/CD28 stimulation of primary C...

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Detalhes bibliográficos
Main Authors: Sgarbanti, Marco, Marsili, Giulia, Remoli, Anna Lisa, Stellacci, Emilia, Mai, Antonello, Rotili, Dante, Perrotti, Edvige, Acchioni, Chiara, Orsatti, Roberto, Iraci, Nunzio, Ferrari, Mathieu, Borsetti, Alessandra, Hiscott, John, Battistini, Angela
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958032/
https://ncbi.nlm.nih.gov/pubmed/24396068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01161-13
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