Identification of a Crucial Residue Required for Staphylococcus aureus LukAB Cytotoxicity and Receptor Recognition

The bicomponent leukotoxins produced by Staphylococcus aureus kill host immune cells through osmotic lysis by forming β-barrel pores in the host plasma membrane. The current model for bicomponent pore formation proposes that octameric pores, comprised of two separate secreted polypeptides (S and F s...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: DuMont, Ashley L., Yoong, Pauline, Liu, Xiang, Day, Christopher J., Chumbler, Nicole M., James, David B. A., Alonzo, Francis, Bode, Nadine J., Lacy, D. Borden, Jennings, Michael P., Torres, Victor J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2014
Pynciau:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958006/
https://ncbi.nlm.nih.gov/pubmed/24379286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01444-13
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