HIV DNA Subspecies Persist in both Activated and Resting Memory CD4(+) T Cells during Antiretroviral Therapy

The latent HIV reservoir is a major impediment to curing HIV infection. The contribution of CD4(+) T cell activation status to the establishment and maintenance of the latent reservoir was investigated by enumerating viral DNA components in a cohort of 12 individuals commencing antiretroviral therap...

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Bibliografiska uppgifter
Huvudupphovsmän: Murray, John M., Zaunders, John J., McBride, Kristin L., Xu, Yin, Bailey, Michelle, Suzuki, Kazuo, Cooper, David A., Emery, Sean, Kelleher, Anthony D., Koelsch, Kersten K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2014
Ämnen:
Pathogenesis and Immunity
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957951/
https://ncbi.nlm.nih.gov/pubmed/24403590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03331-13
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