Enterovirus 2A(pro) Targets MDA5 and MAVS in Infected Cells

RIG-I-like receptors (RLRs) MDA5 and RIG-I are key players in the innate antiviral response. Upon recognition of viral RNA, they interact with MAVS, eventually inducing type I interferon production. The interferon induction pathway is commonly targeted by viruses. How enteroviruses suppress interfer...

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Detalhes bibliográficos
Main Authors: Feng, Qian, Langereis, Martijn A., Lork, Marie, Nguyen, Mai, Hato, Stanleyson V., Lanke, Kjerstin, Emdad, Luni, Bhoopathi, Praveen, Fisher, Paul B., Lloyd, Richard E., van Kuppeveld, Frank J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957915/
https://ncbi.nlm.nih.gov/pubmed/24390337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02712-13
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