Enriching for direct regulatory targets in perturbed gene-expression profiles
Here we build on a previously proposed algorithm to infer direct regulatory relationships using gene-expression profiles from cells in which individual genes are deleted or overexpressed. The updated algorithm can process networks containing feedback loops, incorporate positive and negative regulato...
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| Veröffentlicht in: | Genome Biol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BMC
2004
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395788/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15059262/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/gb-2004-5-4-r29 |
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