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Genomics of KPC-Producing Klebsiella pneumoniae Sequence Type 512 Clone Highlights the Role of RamR and Ribosomal S10 Protein Mutations in Conferring Tigecycline Resistance

Full genome sequences were determined for five Klebsiella pneumoniae strains belonging to the sequence type 512 (ST512) clone, producing KPC-3. Three strains were resistant to tigecycline, one showed an intermediate phenotype, and one was susceptible. Comparative analysis performed using the genome...

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Main Authors: Villa, Laura, Feudi, Claudia, Fortini, Daniela, García-Fernández, Aurora, Carattoli, Alessandra
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957836/
https://ncbi.nlm.nih.gov/pubmed/24379204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01803-13
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