In silico identification and experimental validation of PmrAB targets in Salmonella typhimurium by regulatory motif detection

BACKGROUND: The PmrAB (BasSR) two-component regulatory system is required for Salmonella typhimurium virulence. PmrAB-controlled modifications of the lipopolysaccharide (LPS) layer confer resistance to cationic antibiotic polypeptides, which may allow bacteria to survive within macrophages. The PmrA...

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Detalhes bibliográficos
Main Authors: Marchal, Kathleen, De Keersmaecker, Sigrid, Monsieurs, Pieter, van Boxel, Nadja, Lemmens, Karen, Thijs, Gert, Vanderleyden, Jos, De Moor, Bart
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC395753/
https://ncbi.nlm.nih.gov/pubmed/14759259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2004-5-2-r9
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