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Impaired autophagy in the lipid storage disorder Niemann–Pick type C1 disease
Autophagy dysfunction has been implicated in misfolded protein accumulation and cellular toxicity in several diseases. Whether alterations in autophagy also contribute to the pathology of lipid storage disorders is not clear. Here we show defective autophagy in Niemann-Pick type C1 (NPC1) disease as...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3957429/ https://ncbi.nlm.nih.gov/pubmed/24290752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.10.042 |
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