Impaired autophagy in the lipid storage disorder Niemann–Pick type C1 disease

Autophagy dysfunction has been implicated in misfolded protein accumulation and cellular toxicity in several diseases. Whether alterations in autophagy also contribute to the pathology of lipid storage disorders is not clear. Here we show defective autophagy in Niemann-Pick type C1 (NPC1) disease as...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Sarkar, Sovan, Carroll, Bernadette, Buganim, Yosef, Maetzel, Dorothea, Ng, Alex H.M., Cassady, John, Cohen, Malkiel, Chakraborty, Souvik, Wang, Haoyi, Spooner, Eric, Ploegh, Hidde, Gsponer, Joerg, Korolchuk, Viktor I., Jaenisch, Rudolf
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957429/
https://ncbi.nlm.nih.gov/pubmed/24290752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.10.042
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares