Wordt geladen...

Impaired autophagy in the lipid storage disorder Niemann–Pick type C1 disease

Autophagy dysfunction has been implicated in misfolded protein accumulation and cellular toxicity in several diseases. Whether alterations in autophagy also contribute to the pathology of lipid storage disorders is not clear. Here we show defective autophagy in Niemann-Pick type C1 (NPC1) disease as...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Sarkar, Sovan, Carroll, Bernadette, Buganim, Yosef, Maetzel, Dorothea, Ng, Alex H.M., Cassady, John, Cohen, Malkiel, Chakraborty, Souvik, Wang, Haoyi, Spooner, Eric, Ploegh, Hidde, Gsponer, Joerg, Korolchuk, Viktor I., Jaenisch, Rudolf
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957429/
https://ncbi.nlm.nih.gov/pubmed/24290752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.10.042
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!