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IAPP aggregation and cellular toxicity are inhibited by 1,2,3,4,6-penta-O-galloyl-β-D-glucose

The polyphenol, 1,2,3,4,6-penta-O-galloyl-β-D-glucose (PGG) has been found to exhibit a host of positive pharmacologic activities, including anti-cancer and anti-diabetic. Little is known about the mode of action of PGG in yielding these positive activities. We show here that PGG is a potent inhibit...

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Bibliografiske detaljer
Main Authors: Bruno, Edward, Pereira, Catalina, Roman, Karla P., Takiguchi, Marisa, Kao, Pei-Yu, Nogaj, Luiza A., Moffet, David A.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957415/
https://ncbi.nlm.nih.gov/pubmed/23339420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/13506129.2012.762761
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