Gene Silencing of SOCS3 by siRNA Intranasal Delivery Inhibits Asthma Phenotype in Mice

Suppresors of cytokine signaling (SOCS) proteins regulate cytokine responses and control immune balance. Several studies have confirmed that SOCS3 is increased in asthmatic patients, and SOCS3 expression is correlated with disease severity. The objective of this study was to evaluate if delivering o...

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Main Authors: Mazzeo, Carla, Gámez, Cristina, Rodriguez Marco, Ainara, de Zulueta, Ana, Sanz, Veronica, Bilbao, Izaskun, Ruiz-Cabello, Jesús, Zubeldia, Jose M., del Pozo, Victoria
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956882/
https://ncbi.nlm.nih.gov/pubmed/24637581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091996
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