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HIV-1 Infected Peripheral Blood Mononuclear Cells Modulate the Fibrogenic Activity of Hepatic Stellate Cells through Secreted TGF-β and JNK Signaling

BACKGROUND AND AIMS: Patients with liver disease infected with the human immunodeficiency virus (HIV) exhibit accelerated progression of hepatic fibrosis and liver cirrhosis compared to uninfected individuals. We studied the effects of soluble factors secreted by HIV-infected peripheral blood mononu...

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Detalhes bibliográficos
Main Authors: Gupta, Deepti, Rani, Manjusha, Khan, Nabab, Jameel, Shahid
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956633/
https://ncbi.nlm.nih.gov/pubmed/24637780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091569
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