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The Molecular Basis of Inhibition of Golgi α-Mannosidase II by Mannostatin A
Mannostatin A is a potent inhibitor of the mannose trimming enzyme Golgi α-mannosidase II (GMII), which acts late in the N-glycan processing pathway. Inhibition of this enzyme provides a route to blocking the transformation–associated changes in cancer cell surface oligosaccharide structures. In thi...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3956299/ https://ncbi.nlm.nih.gov/pubmed/19101978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.200800538 |
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