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Human lysosomal α-mannosidases exhibit different inhibition and metal binding properties

Two structurally-related members of the lysosomal mannosidase family, the broad substrate specificity enzyme human lysosomal α-mannosidase (hLM, MAN2B1) and the human core α-1, 6-specific mannosidase (hEpman, MAN2B2) act in a complementary fashion on different glycosidic linkages, to effect glycan d...

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Detalles Bibliográficos
Main Authors: Venkatesan, Meenakshi, Kuntz, Douglas A, Rose, David R
Formato: Artigo
Idioma:Inglês
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788279/
https://ncbi.nlm.nih.gov/pubmed/19722277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.235
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