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Intracellular transport of human lysosomal α-mannosidase and α-mannosidosis-related mutants
Human LAMAN (lysosomal α-mannosidase) was synthesized as a 120 kDa precursor in transfected COS cells [African-green-monkey kidney cells], which was partly secreted as a single-chain form and partly sorted to the lysosomes being subsequently cleaved into three peptides of 70, 40 and 15 kDa respectiv...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1133862/ https://ncbi.nlm.nih.gov/pubmed/15035660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031499 |
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