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Evaluation of PTEN loss and PIK3CA mutations and their correlation with efficacy of trastuzumab treatment in HER2-positive metastatic breast cancer: A retrospective study (KBC-SG 1001)

Trastuzumab (T) has contributed to improving the prognosis of human epidermal growth factor receptor 2 (HER2)-positive breast cancer. Although some patients have been unresponsive or resistant to T. Loss of phosphatase and tensin homolog (PTEN) deleted on chromosome 10, PIK3CA mutation and p95HER2 e...

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書誌詳細
主要な著者: NISHIMURA, REIKI, ARIMA, NOBUYUKI, TOYOSHIMA, SATOSHI, OHI, YASUYO, ANAN, KEISEI, SAGARA, YASUAKI, MITSUYAMA, SHOSHU, TAMURA, KAZUO
フォーマット: Artigo
言語:Inglês
出版事項: D.A. Spandidos 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956249/
https://ncbi.nlm.nih.gov/pubmed/24649121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mco.2012.10
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