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Shift in cytotoxic target from estrogen receptor-positive to estrogen receptor-negative breast cancer cells by trastuzumab in combination with taxane-based chemotherapy

Trastuzumab has shown significant clinical benefits in patients with operable and metastatic HER2-positive breast cancer. However, the biological mechanism of the additional effect of trastuzumab administered in combination with conventional chemotherapy is poorly understood. We performed a retrospe...

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Detalhes bibliográficos
Main Authors: HAYASHI, MITSUHIRO, KAI, KAZUHARU, OKUMURA, YASUHIRO, OSAKO, TOMOFUMI, ARIMA, NOBUYUKI, IWASE, HIROTAKA, NISHIMURA, REIKI
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410577/
https://ncbi.nlm.nih.gov/pubmed/22866081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2011.232
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