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Designer receptor manipulations reveal a role of the locus coeruleus noradrenergic system in isoflurane general anesthesia

Mechanisms driving emergence from general anesthesia are not well understood. The noradrenergic brain nucleus locus coeruleus (LC) modulates arousal and may have effects on general anesthetic state. Using virally delivered designer receptors to specifically control LC norepinephrine (NE) neurons, we...

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Detaylı Bibliyografya
Asıl Yazarlar: Vazey, Elena M., Aston-Jones, Gary
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956184/
https://ncbi.nlm.nih.gov/pubmed/24567395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310025111
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