Autoantibodies to IgG/HLA class II complexes are associated with rheumatoid arthritis susceptibility

Specific HLA class II alleles are strongly associated with susceptibility to rheumatoid arthritis (RA); however, how HLA class II regulates susceptibility to RA has remained unclear. Recently, we found a unique function of HLA class II molecules: their ability to aberrantly transport cellular misfol...

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Hlavní autoři: Jin, Hui, Arase, Noriko, Hirayasu, Kouyuki, Kohyama, Masako, Suenaga, Tadahiro, Saito, Fumiji, Tanimura, Kenji, Matsuoka, Sumiko, Ebina, Kosuke, Shi, Kenrin, Toyama-Sorimachi, Noriko, Yasuda, Shinsuke, Horita, Tetsuya, Hiwa, Ryosuke, Takasugi, Kiyoshi, Ohmura, Koichiro, Yoshikawa, Hideki, Saito, Takashi, Atsumi, Tatsuya, Sasazuki, Takehiko, Katayama, Ichiro, Lanier, Lewis L., Arase, Hisashi
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956152/
https://ncbi.nlm.nih.gov/pubmed/24567378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1401105111
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