Correlation of cyclin D1 and Rb gene expression with apoptosis in invasive breast cancer.

BACKGROUND: In vitro studies have shown that amplification and overexpression of the cyclin D1 gene can accelerate the progress of cells through the G1 phase. Therefore, cyclin D1 may have an apoptosis inhibiting effect. The retinoblastoma (Rb) gene was shown recently to be an important regulator of...

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Bibliographic Details
Main Authors: de Jong, J S, van Diest, P J, Michalides, R J, van der Valk, P, Meijer, C J, Baak, J P
Format: Artigo
Language:Inglês
Published: 1998
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC395605/
https://ncbi.nlm.nih.gov/pubmed/9624417
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