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The neck region of the myosin motor domain acts as a lever arm to generate movement.

The myosin head consists of a globular catalytic domain that binds actin and hydrolyzes ATP and a neck domain that consists of essential and regulatory light chains bound to a long alpha-helical portion of the heavy chain. The swinging neck-level model assumes that a swinging motion of the neck rela...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Uyeda, T Q, Abramson, P D, Spudich, J A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39560/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8633089/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.9.4459
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