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Regulation of glioblastoma stem cells by retinoic acid: role for Notch pathway inhibition

It is necessary to understand mechanisms by which differentiating agents influence tumor-initiating cancer stem cells. Toward this end, we investigated the cellular and molecular responses of glioblastoma stem-like cells (GBM-SCs) to all-trans retinoic acid (RA). GBM-SCs were grown as non-adherent n...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ying, M, Wang, S, Sang, Y, Sun, P, Lal, B, Goodwin, CR, Guerrero-Cazares, H, Quinones-Hinojosa, A, Laterra, J, Xia, S
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955956/
https://ncbi.nlm.nih.gov/pubmed/21383690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.58
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