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A phosphodiesterase 4-controlled switch between memory extinction and strengthening in the hippocampus

Established fear-related memories can undergo phenomena such as extinction or reconsolidation when recalled. Extinction probably involves the creation of a new, competing memory trace that decreases fear expression, whereas reconsolidation can mediate memory maintenance, updating, or strengthening....

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Main Authors: Roesler, Rafael, Reolon, Gustavo K., Maurmann, Natasha, Schwartsmann, Gilberto, Schröder, Nadja, Amaral, Olavo B., Valvassori, Samira, Quevedo, João
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955942/
https://ncbi.nlm.nih.gov/pubmed/24672454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2014.00091
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