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Posttraining systemic administration of the histone deacetylase inhibitor sodium butyrate ameliorates aging-related memory decline in rats

Here we show that a systemic injection of the histone deacetylase inhibitor (HDACi) sodium butyrate (NaB) ameliorated an aging-associated deficit in object recognition memory in rats when the injection was given immediately, but not 6 h after training. NaB had no effect in younger rats with normal m...

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Detalhes bibliográficos
Main Authors: Reolon, Gustavo K., Maurmann, Natasha, Werenicz, Aline, Garcia, Vanessa A., Schröder, Nadja, Wood, Marcelo A., Roesler, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093300/
https://ncbi.nlm.nih.gov/pubmed/21421011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2011.03.033
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