Investigation of an F-18 oxytocin receptor selective ligand via PET imaging

The compound 1-(1-(2-(2-(2-fluoroethoxy)-4-(piperidin-4-yloxy)phenyl)acetyl)piperidin-4-yl)-3,4-dihydroquinolin- 2(1H)-one (1) was synthesized and positively evaluated in vitro for high potency and selectivity with human oxytocin receptors. The positron emitting analogue, [F-18]1, was synthesized an...

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Bibliographic Details
Main Authors:	Smith, Aaron L., Freeman, Sara M., Voll, Ronald J., Young, Larry J., Goodman, Mark M.
Format:	Artigo
Language:	Inglês
Published:	2013
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3955700/ https://ncbi.nlm.nih.gov/pubmed/23978650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.07.045
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Investigation of an F-18 oxytocin receptor selective ligand via PET imaging

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