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The binding epitopes of neurotrophin-3 to its receptors trkC and gp75 and the design of a multifunctional human neurotrophin.

Survival and maintenance of vertebrate neurons are influenced by neurotrophic factors which mediate their signal by binding to specific cell surface receptors. We determined the binding sites of human neurotrophin-3 (NT-3) to its receptors trkC and gp75 by mutational analysis and compared them to th...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Urfer, R, Tsoulfas, P, Soppet, D, Escandón, E, Parada, L F, Presta, L G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395565/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7529173/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06935.x
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