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Disruption of RNA editing in Leishmania tarentolae by the loss of minicircle-encoded guide RNA genes.

RNA editing in kinetoplastids appears to be a labile genetic trait that is affected by prolonged cell culture. The transcripts of the G1-G5 cryptogenes are pan-edited in the recently isolated LEM125 strain of Leishmania tarentolae, but not in the UC strain which has been in culture for 55 years. At...

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Bibliografiske detaljer
Main Authors: Thiemann, O H, Maslov, D A, Simpson, L
Format: Artigo
Sprog:Inglês
Udgivet: 1994
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC395534/
https://ncbi.nlm.nih.gov/pubmed/7988566
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