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Disruption of RNA editing in Leishmania tarentolae by the loss of minicircle-encoded guide RNA genes.

RNA editing in kinetoplastids appears to be a labile genetic trait that is affected by prolonged cell culture. The transcripts of the G1-G5 cryptogenes are pan-edited in the recently isolated LEM125 strain of Leishmania tarentolae, but not in the UC strain which has been in culture for 55 years. At...

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Библиографические подробности
Опубликовано в::EMBO J
Главные авторы: Thiemann, O H, Maslov, D A, Simpson, L
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 1994
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Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395534/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7988566/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06907.x
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