Regulation of mammalian spliceosome assembly by a protein phosphorylation mechanism.

Splicing of mRNA precursors (pre-mRNA) is preceded by assembly of the pre-mRNA with small nuclear ribonucleoprotein particles (snRNPs) and protein factors to form a splicesome. Here we show that stimulating Ser/Thr-specific protein dephosphorylation selectively inhibits an early step during mammalia...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Mermoud, J E, Cohen, P T, Lamond, A I
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395533/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7988565/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06906.x
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