Nuclear export of late HIV-1 mRNAs occurs via a cellular protein export pathway.
The Rev protein of HIV-1 is essential for the nuclear export of incompletely spliced viral mRNAs. This action depends on the mutationally defined Rev activation domain, which both binds the nucleoporin-like human cellular cofactor Rab/hRIP and also functions as a nuclear export signal. Protein kinas...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39553/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8633082/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.9.4421 |
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