Ion Permeability of the Nuclear Pore Complex and Ion-Induced Macromolecular Permeation as Studied by Scanning Electrochemical and Fluorescence Microscopy

[Image: see text] Efficient delivery of therapeutic macromolecules and nanomaterials into the nucleus is imperative for gene therapy and nanomedicine. Nucleocytoplasmic molecular transport, however, is tightly regulated by the nuclear pore complex (NPC) with the hydrophobic transport barriers based...

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Hauptverfasser: Kim, Jiyeon, Izadyar, Anahita, Shen, Mei, Ishimatsu, Ryoichi, Amemiya, Shigeru
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955255/
https://ncbi.nlm.nih.gov/pubmed/24460147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac403607s
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