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Ion Permeability of the Nuclear Pore Complex and Ion-Induced Macromolecular Permeation as Studied by Scanning Electrochemical and Fluorescence Microscopy

[Image: see text] Efficient delivery of therapeutic macromolecules and nanomaterials into the nucleus is imperative for gene therapy and nanomedicine. Nucleocytoplasmic molecular transport, however, is tightly regulated by the nuclear pore complex (NPC) with the hydrophobic transport barriers based...

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Autori principali: Kim, Jiyeon, Izadyar, Anahita, Shen, Mei, Ishimatsu, Ryoichi, Amemiya, Shigeru
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2014
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955255/
https://ncbi.nlm.nih.gov/pubmed/24460147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac403607s
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