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The cytoplasmic domain of CD4 plays a critical role during the early stages of HIV infection in T-cells.

The role played by the cytoplasmic domain of the CD4 molecule in the process of HIV infection was investigated, using A2.01 cells which express different forms of the CD4 gene. A delay in HIV production was consistently observed in cells expressing a truncated CD4 which lacks the cytoplasmic domain...

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Main Authors: Benkirane, M, Jeang, K T, Devaux, C
Formato: Artigo
Idioma:Inglês
Publicado: 1994
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC395519/
https://ncbi.nlm.nih.gov/pubmed/7988553
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