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Radiation redux: Reserve intestinal stem cells miss the call to duty

Distinct stem cell populations in intestinal cryptsmediate tissue homeostasis and responses to epithelial damage such as radiation. Now in Cell Stem Cell, Metcalfe et al. (2014) demonstrate that homeostatic, proliferative Lrg5(+) cells are necessary to regenerate the epithelium after radiation, wher...

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Bibliographic Details
Main Author: Shivdasani, Ramesh A.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955177/
https://ncbi.nlm.nih.gov/pubmed/24506878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2014.01.015
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