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Wnt Secretion from Epithelial Cells and Subepithelial Myofibroblasts Is Not Required in the Mouse Intestinal Stem Cell Niche In Vivo

Wnt signaling is a crucial aspect of the intestinal stem cell niche required for crypt cell proliferation and differentiation. Paneth cells or subepithelial myofibroblasts are leading candidate sources of the required Wnt ligands, but this has not been tested in vivo. To abolish Wnt-ligand secretion...

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Autors principals: San Roman, Adrianna K., Jayewickreme, Chenura D., Murtaugh, L. Charles, Shivdasani, Ramesh A.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923227/
https://ncbi.nlm.nih.gov/pubmed/24527386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2013.12.012
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