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Regulation of organismal proteostasis by trans-cellular chaperone signaling

A major challenge for metazoans is to ensure that different tissues each expressing distinctive proteomes are, nevertheless, well protected at an organismal level from proteotoxic stress. We have examined this and show that expression of endogenous metastable protein sensors in muscle cells induces...

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Bibliografiske detaljer
Main Authors: van Oosten-Hawle, Patricija, Porter, Robert S., Morimoto, Richard I.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955170/
https://ncbi.nlm.nih.gov/pubmed/23746847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.05.015
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