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EphA2 Targeted Chemotherapy Using an Antibody Drug Conjugate in Endometrial Carcinoma

PURPOSE: EphA2 overexpression is frequently observed in endometrial cancers, and is predictive of poor clinical outcome. Here, we utilize an antibody drug conjugate (MEDI-547) composed of a fully human monoclonal antibody against both human and murine EphA2 (1C1) and the tubulin polymerization inhib...

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Detalhes bibliográficos
Main Authors: Lee, Jeong-Won, Stone, Rebecca L., Lee, Sun Joo, Nam, Eun Ji, Roh, Ju-Won, Nick, Alpa M., Han, Hee-Dong, Shahzad, Mian M.K., Kim, Hye-Sun, Mangala, Lingegowda S., Jennings, Nicholas B., Mao, Shenlan, Gooya, John, Jackson, Dowdy, Coleman, Robert L., Sood, Anil K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955167/
https://ncbi.nlm.nih.gov/pubmed/20388851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-0017
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