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Efficient Asymmetric Synthesis of Tryptophan Analogues Having Useful Photophysical Properties

[Image: see text] Two new fluorescent probes of protein structure and dynamics have been prepared by concise asymmetric syntheses using the Schöllkopf chiral auxiliary. The site-specific incorporation of one probe into dihydrofolate reductase is reported. The utility of these tryptophan derivatives...

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Detalhes bibliográficos
Main Authors: Talukder, Poulami, Chen, Shengxi, Arce, Pablo M., Hecht, Sidney M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955165/
https://ncbi.nlm.nih.gov/pubmed/24392870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol403429e
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