Id1 expression promotes peripheral CD4(+) T cell proliferation and survival upon TCR activation without co-stimulation

Although the role of E proteins in the thymocyte development is well documented, much less is known about their function in peripheral T cells. Here we demonstrated that CD4 promoter-driven transgenic expression of Id1, a naturally occurring dominant-negative inhibitor of E proteins, can substitute...

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Main Authors: Liu, Chen, Jin, Rong, Wang, Hong-Cheng, Tang, Hui, Liu, Yuan-Feng, Qian, Xiao-Ping, Sun, Xiu-Yuan, Ge, Qing, Sun, Xiao-Hong, Zhang, Yu
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955101/
https://ncbi.nlm.nih.gov/pubmed/23707719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.05.054
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