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Bone cell-independent benefits of raloxifene on the skeleton: A novel mechanism for improving bone material properties

Raloxifene is an FDA approved agent used to treat bone loss and decrease fracture risk. In clinical trials and animal studies, raloxifene reduces fracture risk and improves bone mechanical properties, but the mechanisms of action remain unclear because these benefits occur largely independent of cha...

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Detalhes bibliográficos
Main Authors: Gallant, Maxime A., Brown, Drew M., Hammond, Max, Wallace, Joseph M., Du, Jiang, Deymier-Black, Alix C., Almer, Jonathan D., Stock, Stuart R., Allen, Matthew R., Burr, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955028/
https://ncbi.nlm.nih.gov/pubmed/24468719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2014.01.009
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