Nanoscale Changes in Collagen are Reflected in Physical and Mechanical Properties of Bone at the Microscale in Diabetic Rats

Diabetes detrimentally affects the musculoskeletal system by stiffening the collagen matrix due to increased advanced glycation end products (AGEs). In this study, tibiae and tendon from Zucker diabetic Sprague-Dawley (ZDSD) rats were compared to Sprague-Dawley derived controls (CD) using Atomic For...

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Detalhes bibliográficos
Main Authors: Hammond, Max A, Gallant, Maxime A, Burr, David B, Wallace, Joseph M
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944921/
https://ncbi.nlm.nih.gov/pubmed/24269519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2013.11.015
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