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Nanoscale Changes in Collagen are Reflected in Physical and Mechanical Properties of Bone at the Microscale in Diabetic Rats

Diabetes detrimentally affects the musculoskeletal system by stiffening the collagen matrix due to increased advanced glycation end products (AGEs). In this study, tibiae and tendon from Zucker diabetic Sprague-Dawley (ZDSD) rats were compared to Sprague-Dawley derived controls (CD) using Atomic For...

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Détails bibliographiques
Auteurs principaux: Hammond, Max A, Gallant, Maxime A, Burr, David B, Wallace, Joseph M
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944921/
https://ncbi.nlm.nih.gov/pubmed/24269519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2013.11.015
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