Inhibition of the liver expression of arylalkylamine N-acetyltransferase increases the expression of angiogenic factors in cholangiocytes

BACKGROUND AND AIMS: Reduction of biliary serotonin N-acetyltransferase (AANAT) expression and melatonin administration/secretion in cholangiocytes increases biliary proliferation and the expression of SR, CFTR and Cl(–)/HCO(3)(–) AE2. The balance between biliary proliferation/damage is regulated by...

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Main Authors: Renzi, Anastasia, Mancinelli, Romina, Onori, Paolo, Franchitto, Antonio, Alpini, Gianfranco, Glaser, Shannon, Gaudio, Eugenio
Formato: Artigo
Idioma:Inglês
Publicado: AME Publishing Company 2014
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954993/
https://ncbi.nlm.nih.gov/pubmed/24696833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2304-3881.2014.01.02
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