Llwytho...

Polyketide Construction via Hydrohydroxyalkylation and Related Alcohol C-H Functionalizations: Reinventing the Chemistry of Carbonyl Addition

Despite the longstanding importance of polyketide natural products in human medicine, nearly all commercial polyketide-based drugs are prepared through fermentation or semi-synthesis. The paucity of manufacturing routes involving de novo chemical synthesis reflects the inability of current methods t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Dechert-Schmitt, Anne-Marie R., Schmitt, Daniel C., Gao, Xin, Itoh, Takahiko, Krische, Michael J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954971/
https://ncbi.nlm.nih.gov/pubmed/24514754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3np70076c
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