Neonatal immune-tolerance in mice does not prevent xenograft rejection

Assessing the efficacy of human stem cell transplantation in rodent models is complicated by the significant immune rejection that occurs. Two recent reports have shown conflicting results using neonatal tolerance to xenografts in rats. Here we extend this approach to mice and assess whether neonata...

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Detalhes bibliográficos
Main Authors: Mattis, Virginia B., Wakeman, Dustin R., Tom, Colton, Dodiya, Hemraj B., Yeung, Sylvia Y., Tran, Andrew H., Bernau, Ksenija, Ornelas, Loren, Sahabian, Anais, Reidling, Jack, Sareen, Dhruv, Thompson, Leslie M., Kordower, Jeffrey H., Svendsen, Clive N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954854/
https://ncbi.nlm.nih.gov/pubmed/24440640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2014.01.007
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